Publications

Dr Manuel S Villareal
Academics and Publications

Dr Manuel S. Villareal has been in private practice for over 24 years in the Northern Kentucky-Cincinnati area.  He is also involved in the academic setting as volunteer faculty in residency/fellowship training programs in the Northern Kentucky-Cincinnati area.  As a Affiliate Associate Clinical Professor of Medicine at the University of Cincinnati College of Medicine he is involved in teaching and training medical students, medical residents and allergy/immunology fellows.  He also serves as volunteer faculty at the St Elizabeth Healthcare, Family Practice Residency Program in Edgewood, Kentucky.

Dr Villareal's has collaborated in several medical articles in allergy, asthma and immunology that have been published  in reputable peer-reviewed medical journals. Listed below are published articles that he has co-authored.

Publications:

Codispoti, CD, Lemasters, GK, Levin, L, Reponen,T, Ryan, PH, Biagini, JM, Villareal, MS, Burkle, J, Evans, S, Lockey, JE, Khurana-Hershey, GK, Bernstein, DI.  Traffic pollution is associated with early childhood aeroallergen sensitization. 
Ann Allergy Asthma Immunol, 2014 Dec 10. pii: S1081-1206(14)00756-X. doi: 10.1016/j.anai.2014.10.020. [Epub ahead of print]

Amin P, Levin L, Epstein T, Ryan P, LeMasters G, Khurana Hershey G, Reponen T, 
Villareal M, Lockey J, Bernstein DI. Optimum predictors of childhood asthma: persistent wheeze or the asthma predictive index? J Allergy Clin Immunol Pract. 2014 Nov-Dec; 2(6):709-715.

Cheng G, Smith AM, Levin L, Epstein T, Ryan PH, LeMasters GK, Khurana Hershey GK, Reponen T,Villareal M, Lockey J, Bernstein DI.  Duration of day care attendance during infancy predicts asthma at the age of seven: the Cincinnati Childhood Allergy and Air Pollution Study.  Clin Exp Allergy. 2014 Oct; 44(10):1274-81
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Epstein TG, Kesavalu B, Bernstein CK, Ryan PH, Bernstein JA, Zimmermann N, Lummus Z, Villareal MS, Smith AM, Lenz PH, Bernstein DI.  Chronic traffic pollution exposure is associated with eosinophilic, but not neutrophilic inflammation in older adult asthmaticsJ Asthma. 2013 Nov 1;50(9):983-9

Reponen T, Lockey J, Bernstein DI, Vesper SJ, Levin L, Khurana Hershey GK, Zheng S, Ryan P, Grinshpun SA, Villareal M, Lemasters G.  Infant origins of childhood asthma associated with specific molds.  J Allergy Clin Immunol. 2012 Sep;130(3):639-644.

Epstein, TG, Ryan, PH, LeMasters, GK, Bernstein, CK, Levin, LS, Bernstein, JA, Villareal, MS, Bernstein, DI.  Poor asthma control and exposure to traffic pollutants and obesity in older adults.  Ann Allergy Asthma Immunol. 2012 June; 108(6):423-428.

Smith AM, Villareal M, Bernstein, DI, Swikert, DJ. Asthma in the elderly: risk factors and impact on physical function. Ann Allergy Asthma Immunol. 2012 May; 108(5): 305-10(E-pub ahead of press).

Biagini Myers JM, Khurana Hershey GK, Deka R, Burkle JW, Levin LS, Bernstein DI, Villareal M, Lockey JE, Reponen T, Gareri J, Lubetsky A, Koren G, LeMasters GK. Asking the right questions to ascertain early childhood secondhand smoke exposures.  Journal of Pediatrics. 2012 April. (E-pub ahead of press).

Brunst KJ, Ryan PH, Lockey JE, Bernstein DI, McKay RT, Khurana Hershey GK,Villareal M, Biagini Myers JM, Levin L, Burkle J, Evans S, Lemasters GK. Unraveling the relationship between aeroallergen sensitization, gender, second-hand smoke exposure, and impaired lung function. Pediatr Allergy Immunol. 2012 Mar 22: 1399-3038

Kim H, Levin L, LeMasters GK, Villareal M, Evans S, Lockey JE, Khurana Hershey GK, Bernstein. Validating childhood symptoms with physician-diagnosed allergic rhinitis.  Ann Allergy Asthma Immunol. 2012 Apr;108(4):228-31. Epub 2012 Feb 28.

Epstein TG, Lemasters GK, Bernstein DI, Ericksen MB, Martin LJ, Ryan PH, Biagini Myers JM, Butsch Kovacic MS, Lindsey MA, He H, Reponen T, Villareal MS, Lockey JE, Bernstein CK, Khurana Hershey GKGenetic variation in small proline rich protein 2B as a predictor for asthma among children with eczema.  Ann Allergy Asthma Immunol. 2012 Mar;108(3):145-150.

Reponen T, Vesper S, Levin L, Johansson E, Ryan P, Burkle J, Grinshpun SA, Zheng S, Bernstein DI, Lockey J, Villareal M, Khurana Hershey GK, LeMasters G. High environmental relative moldiness index during infancy as a predictor of asthma at 7 years of age Ann Allergy Asthma Immunol. 2011 Aug;107(2):120-6. Epub 2011 May 28.

Epstein TG, Bernstein DI, Levin L, Khurana Hershey GK, Ryan PH, Reponen T, Villareal M, Lockey JE, Lemasters GK. Opposing effects of cat and dog ownership and allergic sensitization on eczema in an atopic birth cohort. J Pediatr. 2011 Feb;158(2):265-71.e1-5. 

Codispoti CD, Levin L, LeMasters GK, Ryan P, Reponen T, Villareal M, Burkle J, Stanforth S, Lockey JE, Khurana Hershey GK, Bernstein DI.  Breast-feeding, aeroallergen sensitization, and environmental exposures during infancy are determinants of childhood allergic rhinitis. J Allergy Clin Immunol. 2010 May;125(5):1054-1060.e1. Epub 2010 Apr 14.

Sucharew H, Ryan PH, Bernstein D, Succop P, Khurana Hershey GK, Lockey J, Villareal M, Reponen T, Grinshpun S, LeMasters G. Exposure to traffic exhaust and night cough during early childhood: the CCAAPS birth cohort.  Pediatr Allergy Immunol. 2010 Mar;21(2 Pt 1):253-9. Epub 2009 Oct 12.

Biagini Myers JM, Wang N, LeMasters GK, Bernstein DI, Epstein TG, Lindsey MA, Ericksen MB, Chakraborty R, Ryan PH, Villareal MS, Burkle JW, Lockey JE, Reponen T, Khurana Hershey GK. Genetic and environmental risk factors for childhood eczema development and allergic sensitization in the CCAAPS cohort.  J Invest Dermatol. 2010 Feb;130(2):430-7. Epub 2009 Sep 17.

Schroer KT, Biagini Myers JM, Ryan PH, LeMasters GK, Bernstein DI, Villareal M, Lockey J, Khurana Hershey GK. Associations between Multiple Environmental Exposures and Glutathione S-transferase P1 on Persistent Wheezing in a Birth Cohort.  The Journal of Pediatrics, 2009: March: 154(3), pp. 401-408.

Sucharew H, Succop P, Ryan P, Bernstein D, Khurana Hershey GK, Lockey J, Villareal M, Reponen T, Grinshpun S, LeMasters G.  Exposure to Traffic Exhaust and Recurrent Dry Night Cough During Early Childhood: the CCAAPS Cohort. Submitted for Press. 2009

Iossifova Y, Reponen T, Ryan P, Levin L, Bernstein D, Lockey J, Hershey G, Villareal M, LeMasters G. Mold exposure during infancy as a strong predictor of potential asthma development.  Annals of Allergy, Asthma and Immunology, 2009, vol. 102, no. 2, pp. 131-137.

Smith AM, Bernstein DI, LeMasters GK, Huey NL, Ericksen M, Villareal M, Lockey J, Hershey GKK. Environmental Tobacco Smoke and IL-4 Polymorphism (C-589T) Gene:Environment Interaction Increases Risk of Wheezing in African American Infants.  The Journal of Pediatrics, 2008 May;152(5):709-15, 715.e1. Epub 2007 Dec 21.

Iossifova Y, Reponen T, Bernstein D, Levin L, Kalra H, Campo P, Villareal M, Lockey J, Hershey G, LeMasters G. (2007) House Dust (1-3)-ß-D-Glucan and Wheezing in Infants.
Allergy. 62:504-513.

Vesper, SJ, McKinstry, C, Haugland, RA, Iossifova, Y, LeMasters, G, Levin, L, Khurana Hershey, GK, Villareal, M, Bernstein, DI, Lockey, J, Reponen, T. Relative moldiness index as predictor of childhood respiratory illness. Journal of Exposure Science and Environmental Epidemiology, 2007, pp. 17, 88-94.

Ryan P, LeMasters G, Biswas P, Levin L, Hu S, Lindsey M, Bernstein D, Lockey J, Villareal M, Hershey G, Grinshpun S. (2007) A Comparison of Proximity and Land Use Regression Traffic Exposure Models and Wheezing in Infants.  Environmental Health Perspectives. 115(2):278-284.

Cho S, Reponen, T, LeMasters, G, Levin, L, Huang, J, Meklin, T, Ryan, P, Villareal, M, Bernstein, D. Mold Damage in homes and wheezing in infants. Annals of Allergy, Asthma and Immunology, 2006, vol. 97, no. 4, pp. 539-545.

LeMasters GK, Wilson K, Levin L, Biagini J, Ryan PH, Lockey JE, Stanforth S, Maier S, Yang J, Burkle J, Villareal M, Hershey GKK, Bernstein DI. (2006) High Prevalence of Aeroallergen Sensitization Among Infants of Atopic Parents. The Journal of Pediatrics. 149:505-111.


Biagini,J, LeMasters, G, Ryan, PH, Levin, L, Reponen, T, Bernstein, D, Villareal, M,Khurana Hershey, G Burkle,        J, Lockey, J.  Environmental risk factors in early Infancy.Pediatric Allergy and Immunology, June 2006. 17(4):278-284.

Campo, P, Kalra, H, Levin, L, Reponen, T, Olds, R, Lummus, Z, Seung-Hyun, C, Khurana Hershey, G, Lockey, J, Villareal, M, Stanforth, S, LeMasters, G, Bernstein, DI. (2006)  Influence Of Dog Ownership and High Endotoxin on Wheezing and Atopy during Infancy.  Journal of Allergy and Clinical Immunology. 118(6):1271-8


Ryan PH, LeMasters G, Biagini J, Bernstein D, Grishpun SA, Shukla R, Wilson K, Villareal M, Burkle J,  Lockey J.  Is it Traffic type, volume or distance?  Wheezing in infants living near truck and bus traffic. JAllergy Clin Immunology, August 2005; 116:279-84

White, JF, Bernstein, D, Villareal, M, Bernstein, IL, Bernstein, J, St. Clarie, H. A Correlation of Ambient Tree Pollen Exposure and In Vivo Antigen Sensitivity in Patients with Seasonal Allergic Rhinitis. Annals of Allergy, Asthma & Immunology.
Annals of Allergy, Asthma & Immunology.  Feb 2005.94(2): 240-6.

Lang, DM, Vinstainer PF, Howland WC, Villareal MS.  Survey of the Extent and Nature of Care for Adults and Older Adults by Allergy/Immunology Practitioners.  Annals of Allergy, Asthma and Immunology, August 2000.

Villareal MS, Gordon EH, Klaustermeyer WB, Hahn T.  Osteoporosis and Steroid-dependent Asthma.  Annals of Allergy, Asthma and Immunology, April 1996.

 

 

 

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